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Monografia: Sanprobi® Stress

Karolina Skonieczna-Żydecka Maria Marlicz




W tym numerze czasopisma "Współczesna Dietetyka" prezentujemy kolejny artykuł z cyklu monografie. Tym razem zaprezentujemy preparat Sanprobi® Stress oraz właściwości szczepów bakteryjnych w nim zawartych.


1. Carabotti M., Scirocco A., Maselli M.A., Severi C., The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems, "Ann Gastroenterol." 28(2), 2015, 203–209.

2. By the numbers: Our stressed-out nation [Internet]. [cited 2018 Aug 8]. Available from:

3. Anderson N.B., Belar C.D., Breckler S.J., Nordal K.C., Ballard D.W., Bufka L.F. et al., American Psychological Association, 2013.

4. Press release [Internet]. 2018 [cited 2018 Aug 12]. Available from:

5. Stachowska E., Maciejewska D., Ryterska K., Baszuk P., Skonieczna-Żydecka K., Czerwińska-Rogowska M. et al., Defecation-related abdominal pain is frequent among young people - a population based study in young participants of Woodstock rock festival in Poland, "J Gastro Live Dis.".

6. Epel E.S., Prather A.A., Stress, Telomeres, and Psychopathology: Toward a Deeper Understanding of a Triad of Early Aging, "Annu Rev Clin Psychol." 7(14), 2018, 371–397.

7. Fischer A., Ziogas A., Anton-Culver H., Perception matters: Stressful life events increase breast cancer risk, "J Psychosom Res." Jul 2018,110, 46–53.

8. Van der Valk E.S., Savas M. Van Rossum E.F.C., Stress and Obesity: Are There More Susceptible Individuals? "Curr Obes Rep." 7(2), 2018, 193–203.

9. Kivimäki M., Steptoe A., Effects of stress on the development and progression of cardiovascular disease, "Nature Reviews Cardiology" 15(4), 2018, 215–229.

10.       Yang L., Zhao Y., Wang Y., Liu L., Zhang X., Li B. et al., The Effects of Psychological Stress on Depression, "Curr Neuropharmacol." 13(4), 2015, 494–504.

11.       Landowski J.,Neurobiology of stress, "Neuropsychiatria i Neuropsychologia" 2(1), 2007, 26–36.

12.       Spadoni I., Zagato E., Bertocchi A., Paolinelli R., Hot E., Di Sabatino A. et al., A gut-vascular barrier controls the systemic dissemination of bacteria, "Science" 13, 350(6262), 2015, 830–834.

13.       Marlicz W., Loniewski I., Koulaouzidis A., Gut vascular barrier and chronic disease, "Science"; e-letter 2016. Available from :

14.       Foster J.A., Rinaman L., Cryan J.F., Stress & the gut-brain axis: Regulation by the microbiome, "Neurobiology of Stress" 1(7), 2017, 124–136.

15.       Hill C., Guarner F., Reid G., Gibson G.R., Merenstein D.J., Pot B. et al., Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic, "Nat Rev Gastroenterol Hepatol." 11(8), 2014, 506–514.

16.       Dinan T.G., Stanton C., Cryan J.F., Psychobiotics: a novel class of psychotropic, "Biol Psychiatry" 15, 74(10), 2013, 720–726.

17.       Update of the list of QPS-recommended biological agents intentionally added to food or feed as notified to EFSA 6: suitability of taxonomic units notified to EFSA until March 2017 [Internet]. European Food Safety Authority. 2017 [cited 2018 Aug 7]; Available from:

18.       Bourdichon F., Casaregola S., Farrokh C., Frisvad J.C., Gerds M.L., Hammes W.P. et al., Food fermentations: microorganisms with technological beneficial use, "Int J Food Microbiol." 15, 154(3), 2012, 87–97.

19.       Administration AGD of HTG. Australian regulatory guidelines for complementary medicines (ARGCM) [Internet]. Therapeutic Goods Administration (TGA). 2018 [cited 2018 Aug 12]; Available from:

20.       Five Probiotic Formulations from Lallemand Granted Health Claims by Health Canada [Internet]. [cited 2018 Aug 8]; Available from:

21.       Mikrobiota jelitowa jako potencjalna przyczyna zaburzeń funkcjonowania emocjonalnego człowieka – CPM [Internet]. [cited 2018 Aug 8]; Available from:

22.       Zareie M., Johnson‐Henry K., Jury J., Yang P., Ngan B., McKay D.M. et al., Probiotics prevent bacterial translocation and improve intestinal barrier function in rats following chronic psychological stress, "Gut" 55(11), 2006, 1553–1560.

23.       Gareau M.G., Jury J., MacQueen G., Sherman P.M., Perdue M.H., Probiotic treatment of rat pups normalises corticosterone release and ameliorates colonic dysfunction induced by maternal separation, "Gut" 56(11), 2007, 1522–1528.

24.       Messaoudi M., Lalonde R., Violle N., Javelot H., Desor D., Nejdi A. et al., Assessment of psychotropic-like properties of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects, "Br J Nutr." 105(5), 2011, 755–764.

25.       Gareau M.G., Wine E., Reardon C., Sherman P.M., Probiotics Prevent Death Caused by Citrobacter rodentium Infection in Neonatal Mice, "J Infect Dis." 1, 201(1), 2010, 81–91.

26.       Gareau M.G., Wine E., Rodrigues D.M., Cho J.H., Whary M.T., Philpott D.J. et al., Bacterial infection causes stress-induced memory dysfunction in mice, "Gut" 60(3), 2011, 307–317.

27.       Girard S.A., Bah T.M., Kaloustian S., Lada-Moldovan L., Rondeau I., Tompkins T.A. et al., Lactobacillus helveticus and Bifidobacterium longum taken in combination reduce the apoptosis propensity in the limbic system after myocardial infarction in a rat model, "Br J Nutr." 102(10), 2009, 1420–1425.

28.       Arseneault-Bréard J., Rondeau I., Gilbert K., Girard S.A., Tompkins T.A., Godbout R. et al., Combination of Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 reduces post-myocardial infarction depression symptoms and restores intestinal permeability in a rat model, "Br J Nutr." 107(12), 2012, 1793–1799.

29.       Ohland C.L., Kish L., Bell H., Thiesen A., Hotte N., Pankiv E. et al., Effects of Lactobacillus helveticus on murine behavior are dependent on diet and genotype and correlate with alterations in the gut microbiome, "Psychoneuroendocrinology" 38(9), 2013, 1738–1747.

30.       Ait-Belgnaoui A., Colom A., Braniste V., Ramalho L., Marrot A., Cartier C. et al., Probiotic gut effect prevents the chronic psychological stress-induced brain activity abnormality in mice, "Neurogastroenterol Motil." 26(4), 2014, 510–520.

31.       Callaghan B.L., Cowan C.S.M., Richardson R., Treating Generational Stress: Effect of Paternal Stress on Development of Memory and Extinction in Offspring Is Reversed by Probiotic Treatment, "Psychol Sci." 27(9), 2016, 1171–1180.

32.       Ait-Belgnaoui A., Payard I., Rolland C., Harkat C., Braniste V., Théodorou V. et al., Bifidobacterium longum and Lactobacillus helveticus Synergistically Suppress Stress-related Visceral Hypersensitivity Through Hypothalamic-Pituitary-Adrenal Axis Modulation, "J Neurogastroenterol Motil." 30, 24(1), 2018, 138–146.

33.       Verdu E.F., Bercik P., Huang X.X., Lu J., Al-Mutawaly N., Sakai H. et al., The role of luminal factors in the recovery of gastric function and behavioral changes after chronic Helicobacter pylori infection, "Am J Physiol Gastrointest Liver Physiol." 295(4), 2008, 664-670.

34.       Emge J.R., Huynh K., Miller E.N., Kaur M., Reardon C., Barrett K.E. et al., Modulation of the microbiota-gut-brain axis by probiotics in a murine model of inflammatory bowel disease, "Am J Physiol Gastrointest Liver Physiol." 1, 310(11), 2016, 989–998.

35.       Cowan C.S.M., Callaghan B.L., Richardson R., The effects of a probiotic formulation (Lactobacillus rhamnosus and L. helveticus) on developmental trajectories of emotional learning in stressed infant rats, "Transl Psychiatry" 31, 6(5), 2016, 823.

36.       Gilbert K., Arseneault-Bréard J., Flores Monaco F., Beaudoin A., Bah T.M., Tompkins T.A. et al., Attenuation of post-myocardial infarction depression in rats by n-3 fatty acids or probiotics starting after the onset of reperfusion, "Br J Nutr." 14, 109(1), 2013, 50–56.

37.       Malick M., Gilbert K., Daniel J., Arseneault-Breard J., Tompkins T.A., Godbout R. et al., Vagotomy prevents the effect of probiotics on caspase activity in a model of postmyocardial infarction depression, "Neurogastroenterol Motil." 27(5), 2015, 663–71.

38.       Diop L., Guillou S., Durand H., Probiotic food supplement reduces stress-induced gastrointestinal symptoms in volunteers: a double-blind, placebo-controlled, randomized trial, "Nutr Res." 28(1), 2008, 1–5.

39.       Messaoudi M., Violle N., Bisson J.F., Desor D. Javelot H., Rougeot C., Beneficial psychological effects of a probiotic formulation (Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in healthy human volunteers, "Gut Microbes" 2(4), 2011, 256–261.

40.       Romijn A.R., Rucklidge J.J., Kuijer R.G., Frampton C., A double-blind, randomized, placebo-controlled trial of Lactobacillus helveticus and Bifidobacterium longum for the symptoms of depression, "Aust N Z J Psychiatry" 51(8), 2017, 810–821.

O autorze

Karolina Skonieczna-Żydecka


Zakład Biochemii i Żywienia Człowieka, Pomorski Uniwersytet Medyczny w Szczecinie

Maria Marlicz


Sanprobi Sp. z o.o. sp.k.